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Not only that, some studies reported that the transcription factors, Oct-4 and Nanog in CSC can positively regulate the EMT and metastasis process of breast cancer patients, Nanog induces squamous cell carcinoma metastasis through EMT-related promoters such as ZEB1 and ZEB2 (133, 134)

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Curcumin Curcumin is a yellow dye first isolated from turmeric ( Curcuma longa ) in the 19th century by Vogel et Pelletier [58]